Highlight | Molecular mechanisms
Zinc is involved in certain diseases (neurodegenerative, cancer ...). Researchers from the Chemistry and Biology of Metals Laboratory have recently shown that an ion channel (TRPC6) facilitates the import of zinc and when the protein is overexpressed, increases the pool size of the metal trapped in internal compartments of the cell. Finally, overexpression of TRPC6 is accompanied by increased expression of proteins related to the actin cytoskeleton, and changes the cellular architecture.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.