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Press release | Cytoskeleton

Mimicking the living to study cellular contractile mechanisms


​​​​Due to the design of a device mimicking a cell skeleton or cytoskeleton, researchers from the CEA CNRS and Université Joseph-Fourier could for the first time decipher some of the organizational laws defining the architecture of cells. These investigators have shown that motor molecules, the myosins, were responsible for the selective contraction of certain intracellular structures formed by actin, an abundantly protein in the cells. The highlight mechanism allows to understand how the generation of forces inside the cells can be locally modulated in a very accurately way. These results open new perspectives, especially for the understanding of dysfunctions observed in some serious diseases like cancer.​

Published on 7 June 2012

​This work is published online June 7 by the journal Science.

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